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Literature Cited

Acree TE.  1997.  GC/Olfactometry. Anal Chem 170A-175A.

Alarie Y.  1973.  Sensory irritation by airborne chemicals. CRC Crit Rev Toxicol 2:299-363.

Araneda RC, Kini AD, Firestein S. 2000. The molecular receptive range of an odorant receptor. Nat Neurosci 3:1248-55.

Arctander S. 1994. Perfume and Flavor Chemicals (Aroma Chemicals). Carol Stream, IL: Allured Publishing Company.

Aungst JL, Heyward PM, Puche AC, Karnup SV, Hayar A, Szabo G, Shipley MT. 2003. Centre-surround inhibition among olfactory bulb glomeruli. Nature 426:623-629.

Buck L, Axel R. 1991. A novel multigene family may encode odorant receptors: A molecular basis for odor recognition. Cell 65:175-187.

Cinelli AR, Hamilton KA, Kauer JS. 1995. Salamander olfactory bulb neuronal activity observed by video rate, voltage-sensitive dye imaging. III. Spatial and temporal properties of responses evoked by odorant stimulation. J Neurophysiol 73:2053-71

Cleland TA, Morse A, Yue EL, Linster C. 2002. Behavioral models of odor similarity. Behav Neurosci 116:222-231.

Coopersmith R, Leon M. 1984. Enhanced neural response to familiar olfactory cues. Science 225:849-851.

Coopersmith R, Leon M. 1986. Enhanced neural response by adult rats to odors experienced early in life. Brain Res 371:400-403.

Coopersmith R, Henderson SR, Leon M. 1986. Odor specificity of the enhanced neural response following early odor experience in rats. Dev Brain Res 27:191-197.

Dravnieks A. 1985. Atlas of odor character profiles. Philadelphia: ASTM Data Series DS 61.

Dreher JG, Rouseff RL, Naim M. 2003. GC-olfactometric characterization of aroma volatiles from the thermal degradation of thiamin in model orange juice. J Agric Food Chem 51:3097-3102.

Fletcher ML, Wilson DA. 2003. Olfactory bulb mitral-tufted cell plasticity: odorant-specific tuning reflects previous odorant exposure. J Neurosci 23:6946-55.

Friedrich RW, Korsching SI. 1997. Combinatorial and chemotopic odorant coding in the zebrafish olfactory bulb visualized by optical imaging. Neuron 18:737-52.

Fuss SH, Korsching SI. 2001. Odorant feature detection: activity mapping of structure response relationships in the zebrafish olfactory bulb. J Neurosci 21:8396-407.

Galizia CG, Sachse S, Rappert A, Menzel R. 1999. The glomerular code for odor representation is species specific in the honeybee Apis mellifera. Nat Neurosci 2:473-8.

Guthrie KM, Gall CM. 1995.  Functional mapping of odor-activated neurons in the olfactory bulb. Chem Senses 20:271-282.

Hass HB, Newton RF. 1975. Correction of boiling points to standard pressure. In Weast RC (ed): Handbook of Chemistry and Physics. 56th ed. Cleveland, Ohio: CRC Press, pp. D176-D177.

Ho SL, Johnson BA, Leon M. 2006. Long hydrocarbon chains serve as unique molecular features recognized by ventral glomeruli of the rat olfactory bulb. J Comp Neurol 498:16-30.

Hornung DE, Mozell MM. 1977. Factors influencing the differential sorption of odorant molecules across the olfactory mucosa. J Gen Physiol 69:343-361.

Imamura K, Mataga N, Mori K.  1992.  Coding of odor molecules by mitral/tufted cells in rabbit olfactory bulb. I. Aliphatic compounds. J Neurophysiol 68:1986-2002.

Johnson BA, Leon M. 1996. Spatial distribution of [14C]2-deoxyglucose uptake in the glomerular layer of the rat olfactory bulb following early odor preference learning. J Comp Neurol 376:557-66.

Johnson BA, Leon M. 2000a. Modular representations of odorants in the glomerular layer of the rat olfactory bulb and the effects of stimulus concentration. J Comp Neurol 422:496-509.

Johnson BA, Leon M. 2000b. Odorant molecular length: one aspect of the olfactory code. J Comp Neurol 426:330-338.

Johnson BA, Leon M. 2001. Spatial coding in the olfactory system: the role of early experience. In: Blass EM, ed, Developmental Psychobiology, Kluwer Academic/Plenum Publishers, New York, pp 53-76.

Johnson BA, Woo CC, Duong H, Nguyen V, Leon M. 1995. A learned odor evokes an enhanced Fos-like glomerular response in the olfactory bulb of young rats. Brain Res 699:192-200.

Johnson BA, Woo CC, Leon M. 1998. Spatial coding of odorant features in the glomerular layer of the rat olfactory bulb. J Comp Neurol 393:457-471.

Johnson BA, Woo CC, Hingco EE, Pham KL, Leon M. 1999. Multidimensional chemotopic responses to n-aliphatic acid odorants in the rat olfactory bulb. J Comp Neurol 409:529-548.

Johnson BA, Ho SL, Xu Z, Yihan JS, Yip S, Hingco EE, Leon M.  2002.  Functional mapping of the rat olfactory bulb using diverse odorants reveals modular responses to functional groups and hydrocarbon structural features.  J Comp Neurol 449:180-194.

Johnson BA, Farahbod H, Xu Z, Saber S, Leon M.  2004.  Local and global chemotopic organization: general features of the glomerular representations of aliphatic odorants differing in carbon number.  J Comp Neurol, 480:234-49.

Johnson BA, Farahbod H, Saber S, Leon M.  2005a.  Effects of functional group position on spatial representations of aliphatic odorants in the rat olfactory bulb. J Comp Neurol, 483, 192-204.

Johnson BA, Farahbod H, Leon M.  2005b. Interactions between odorant functional group and hydrocarbon structure influence activity in glomerular response modules in the rat olfactory bulb. J Comp Neurol, 483, 205-216.

Kauer JS, Cinelli AR. 1993. Are there structural and functional modules in the vertebrate olfactory bulb? Micr Res Tech 24:157-167.

Kennedy C, Des Rosiers MH, Jehle JW, Reivich M, Sharpe F, Sokoloff L. 1975. Mapping of functional neural pathways by autoradiographic survey of local metabolic rate with (14C)deoxyglucose. Science 187: 850-3.

Leon M. 1987. Plasticity of olfactory output circuits related to early olfactory learning. Trends Neurosci 10:434-438.

Linster C, Johnson BA, Yue E, Morse A, Xu Z, Hingco E, Choi Y, Choi M, Messiha A, Leon M. 2001. Perceptual correlates of neural representations evoked by odorant enantiomers. J Neurosci 21:9837-9843.

Linster C, Johnson BA, Morse A, Yue E, Leon M.  2002.  Spontaneous versus reinforced olfactory discriminations.  J Neurosci 22:6842-6845.

Lu X-C M, Slotnick BM. 1994. Recognition of propionic acid vapor after removal of the olfactory bulb area associated with high 2-DG uptake. Brain Res 639:26-32.

Lu X-C M, Slotnick BM. 1998. Olfaction in rats with extensive lesions of the olfactory bulbs: Implications for odor coding. Neuroscience 84:849-866.

Lunden A, Gustafsson V, Imhof M, Gauch R, Bosset J-O. 2002. High trimethylamine concentration in milk from cows on standard diets is expressed as fishy off-flavor. J Dairy Res 69:383-390.

Malnic B, Hirono J, Sato T, Buck LB. 1999.  Combinatorial receptor codes for odors.  Cell 96:713-723.

Matsutani S, Leon M. 1993. Elaboration of glial processes in the rat olfactory bulb associated with early olfactory learning. Brain Res 613:317-320.

McCollum JF, Woo CC, Leon M. 1997. Granule and mitral cell densities are unchanged following early olfactory preference training. Dev Brain Res 99:118-120.

Meister M, Bonhoeffer T.  2001. Tuning and topography in an odor map on the rat olfactory bulb. J Neurosci 21:1351-1360.

Mombaerts P, Wang F, Dulac C, Chao SK, Nemes A, Mendelsohn M, Edmonson J, Axel R. 1996. Visualizing an olfactory sensory map. Cell 87:675-686.

Mori K, Shepherd GM. 1994. Emerging principles of molecular signal processing by mitral/tufted cells in the olfactory bulb. Semin Cell Biol 5:65-74.

Mori K, Mataga N, Imamura K. 1992. Differential specificities of single mitral cells in rabbit olfactory bulb for a homologous series of fatty acid odor molecules. J Neurophysiol 67:786-789.

Motokizawa F. 1996. Odor representation and discrimination in mitral/tufted cells of the rat olfactory bulb. Exp Brain Res 112:24-34.

Mozell MM. 1964. Evidence for sorption as a mechanism of the olfactory analysis of vapors. Nature 203:1181-2.

Mozell MM, Sheehe PR, Hornung DE, Kent PF, Youngentob SL, Murphy SJ. 1987. “Imposed” and “inherent” mucosal activity patterns. J Gen Physiol 90:625-650.

Polak EH.  1973.  Multiple profile-multiple receptor site model for vertebrate olfaction. J Theor Biol 40:469-484.

Ressler KJ, Sullivan SL, Buck LB. 1993. A zonal organization of odorant receptor gene expression in the olfactory epithelium. Cell 73:597-609.

Ressler KJ, Sullivan SL, Buck LB. 1994. Information coding in the olfactory system: evidence for a stereotyped and highly organized epitope map in the olfactory bulb. Cell 79:1245-1255.

Rinberg D, Koulakov A, Ollinger F, Gelperin A. 2004. Mitral cell responses in awake and anesthetized mice. Program No. 139.11. Abstract Viewer/Itinerary Planner. Washington, DC: Society for Neuroscience, 2004. Online.

Royet JP, Sicard G, Souchier C, Jourdan F. 1987.  Specificity of spatial patterns of glomerular activation in the mouse olfactory bulb: Computer-assisted image analysis of 2-deoxyglucose autoradiograms. Brain Res 417:1-11.

Rubin BD, Katz LC. 1999. Optical imaging of odorant representations in the mammalian olfactory bulb. Neuron 23:499-511.

Sachse S, Rappert A, Galizia CG. 1999. The spatial representation of chemical structures in the antennal lobe of honeybees: steps towards the olfactory code. Eur J Neurosci 11:3970-82.

Schoenfeld TA, Knott TK. 2002. NADPH diaphorase activity in olfactory receptor neurons and their axons conforms to a rhinotopically-distinct dorsal zone of the hamster nasal cavity and main olfactory bulb. J Chem Neuroanat 24:269-85.

Schoenfeld TA, Knott TK. 2004.  Evidence for the disproportionate mapping of olfactory airspace onto the main olfactory bulb of the hamster.  J Comp Neurol 476:186-201.

Schoenfeld TA, Clancy AN, Forbes WB, Macrides F. 1994. The spatial organization of the peripheral olfactory system of the hamster. I. Receptor neuron projections to the main olfactory bulb. Brain Res Bull 34:183-210.

Slotnick BM, Panhuber H, Bell GA, Laing DG. 1989. Odor-induced metabolic activity in the olfactory bulb of rats trained to detect propionic acid vapor. Brain Res 500:161-168.

Spors H, Grinvald A. 2002. Spatio-temporal dynamics of odor representations in the mammalian olfactory bulb. Neuron 34:301-315.

Stewart WB, Kauer JS, Shepherd GM 1979. Functional organization of rat olfactory bulb analysed by the 2-deoxyglucose method. J Comp Neurol 185:715-34.

Strotmann J, Wanner I, Krieger J, Raming K, Breer H. 1992. Expression of odorant receptors in spatially restricted subsets of chemosensory neurones. Neuroreport 3:1053-6.

Strotmann J, Conzelmann S, Beck A, Feinstein P, Breer H, Mombaerts P. 2000. Local permutations in the glomerular array of the mouse olfactory bulb. J Neurosci 20:6927-38.

Sullivan RM, Leon M. 1986. Early olfactory learning induces an enhanced neural response in young rats. Dev Brain Res 27:278-282.

Sullivan RM, Wilson DA, Kim MH, Leon M. 1990. Modified behavioral and olfactory bulb responses to maternal odors in preweanling rats. Dev Brain Res 53:243-247.

Takahashi YK, Kurosaki M, Hirono S, Mori K. 2004. Topographic representation of odorant molecular features in the rat olfactory bulb. J Neurophysiol 92:2413-27.

Treloar HB, Feinstein P, Mombaerts P, Greer CA.  2002.  Specificity of glomerular targeting by olfactory sensory axons.  J Neurosci  22:2469-2477.

Uchida N, Takahashi YK, Tanifuji M, Mori K. 2000. Odor maps in the mammalian olfactory bulb: domain organization and odorant structural features. Nat Neurosci 3:1035-1043.

Vassar R, Ngai J, Axel R. 1993. Spatial segregation of odorant receptor expression in the mammalian olfactory epithelium. Cell 74:309-18.

Vassar R, Chao SK, Sitcheran R, Nuñez JM, Vosshall LB, Axel R. 1994. Topographic organization of sensory projections to the olfactory bulb. Cell 79:981-991.

Wachowiak M, Cohen LB. 2001. Representation of odorants by receptor neuron input to the mouse olfactory bulb. Neuron 32:723-735.

Wachowiak M, Cohen LB.  2003.Correspondence between odorant-evoked patterns of receptor neuron input and intrinsic optical signals in the mouse olfactory bulb.  J Neurophysiol. 89:1623-1639.

Wilson DA, Sullivan RM, Leon M. 1987. Single-unit analysis of postnatal olfactory learning: modified olfactory bulb output response patterns to learned attractive odors. J Neurosci 7:3154-3162.

Woo CC, Leon M. 1991. Increase in a focal population of juxtaglomerular cells in the olfactory bulb associated with early olfactory learning. J Comp Neurol 305:49-56.

Woo CC, Leon M. 1995. Early olfactory enrichment and deprivation both decrease beta-adrenergic receptor density in the main olfactory bulb of the rat. J Comp Neurol 360:634-642.

Woo CC, Coopersmith R, Leon M. 1987. Localized changes in olfactory bulb morphology associated with early olfactory learning. J Comp Neurol 263:113-125.

Woo CC, Oshita MH, Leon M. 1996. A learned odor decreases the number of Fos-immunopositive granule cells in the olfactory bulb of young rats. Brain Res 716:149-156.

Xu F, Kida I, Hyder F, Shulman RG. 2000. Assessment and discrimination of odor stimuli in rat olfactory bulb by dynamic functional MRI. Proc Natl Acad Sci USA 97:10601-6.

Yokoi M, Mori K, Nakanishi S.  1995.  Refinement of odor molecule tuning by dendrodendritic synaptic inhibition in the olfactory bulb. Proc Natl Acad Sci USA 92:3371-3375.


Mapping Data
Combinatorial Coding
Molecular Features
Glomerular Modules
Chemotopic Progressions
Global Chemotopy
Feature Interactions
Predictive Value
Odorant Concentration
Odorant Contaminants
Effects of Experience
Literature Cited


This Human Brain Project/Neuroinformatics project is funded by the National Institute on Deafness and Other Communication Disorders and the National Institute of Mental Health